Metamizole
Based on 2 publication(s) in Google Scholar
Metamizol (Methamizole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 50567-35-6
- 分子式: C13H17N3O4S
- 分子量:311.36
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
MedChemExpress(MCE)の使用を引用している文献 Metamizole
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生物活性
Metamizo (100 mg/kg; i.p.; once; male Swiss albino mice) causes a decrease in hepatic glutathione (GSH) contents[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Swiss albino mice (6 weeks old, 25-40 g)[1]
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Dosage:100 mg/kg
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Administration:Intraperitoneal injection; once
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Result:Increased serum ALT level at 5 hours and the maximum serum ALT levels occurred at 5 hours.
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Animal Model:Male Swiss albino mice (6 weeks old, 25-40 g)[1]
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Dosage:100 mg/kg
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Administration:Intraperitoneal injection; once
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Result:Induced reduction in hepatic glutathione (GSH) content in mice.
化学情報
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CAS 番号 50567-35-6
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分子量 311.36
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分子式 C13H17N3O4S
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SMILES
O=C1C(N(CS(=O)(O)=O)C)=C(C)N(C)N1C2=CC=CC=C2
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別名
Dipyrone free base; Methamizole
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Int J Biol Macromol
Reticuline isomerase AKR1B1 with aldo-keto reductase activity and detoxification function from the insect Blaps rhynchopetera. [Abstract]2026 Mar:352:151224. PMID: 41791543 -
Animal Model Exp Med
Experimental study of a novel mouse model of tibial shaft fracture combined with blunt chest trauma. [Abstract]2025 Apr;8(4):696-706. PMID: 38225728
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)