Metamizole
Based on 2 publication(s) in Google Scholar
Metamizol (Methamizole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity.
It is advisable to consider the stable salt form (Metamizole sodium) that retains the same biological activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 50567-35-6
- 分子式: C13H17N3O4S
- 分子量:311.36
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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MedChemExpress（MCE）の使用を引用している文献 Metamizole
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生物活性
製品説明
体内実験
Metamizo (100 mg/kg; i.p.; once; male Swiss albino mice) causes a decrease in hepatic glutathione (GSH) contents[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Swiss albino mice (6 weeks old, 25-40 g)[1]
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Dosage:100 mg/kg
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Administration:Intraperitoneal injection; once
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Result:Increased serum ALT level at 5 hours and the maximum serum ALT levels occurred at 5 hours.
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Animal Model:Male Swiss albino mice (6 weeks old, 25-40 g)[1]
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Dosage:100 mg/kg
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Administration:Intraperitoneal injection; once
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Result:Induced reduction in hepatic glutathione (GSH) content in mice.
化学情報
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CAS 番号 50567-35-6
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分子量 311.36
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分子式 C13H17N3O4S
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SMILES
O=C1C(N(CS(=O)(O)=O)C)=C(C)N(C)N1C2=CC=CC=C2
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別名
Dipyrone free base; Methamizole
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Int J Biol Macromol
Reticuline isomerase AKR1B1 with aldo-keto reductase activity and detoxification function from the insect Blaps rhynchopetera. [Abstract]2026 Mar:352:151224. PMID: 41791543 -
Animal Model Exp Med
Experimental study of a novel mouse model of tibial shaft fracture combined with blunt chest trauma. [Abstract]2025 Apr;8(4):696-706. PMID: 38225728
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Metamizole 関連分類
HY-148147 関連分類
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