(-)-7-Methoxyrosmanol
Based on 1 Customer Validation
(-)-7-Methoxyrosmanol ((-)-7-O-Methoxyrosmanol) is a phenolic diterpene with antioxidant activity. (-)-7-Methoxyrosmanol is produced from carnosic acid by oxidation and cyclization, can induce cell cycle arrest and apoptosis in neuroblastoma cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.53%
- CAS 番号: 24703-38-6
- 分子式: C21H28O5
- 分子量:360.44
-
保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
35.6 μM
Compound: 7
|
Cytotoxicity against human A549 cells at lag phase of growth after 48 hrs by MTT assay
Cytotoxicity against human A549 cells at lag phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| A549 | IC50 |
50.8 μM
Compound: 7
|
Cytotoxicity against human A549 cells at exponential phase of growth after 48 hrs by MTT assay
Cytotoxicity against human A549 cells at exponential phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| HeLa | IC50 |
>60 μM
Compound: 7
|
Cytotoxicity against human HeLa cells at exponential phase of growth after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells at exponential phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| HeLa | IC50 |
40.8 μM
Compound: 7
|
Cytotoxicity against human HeLa cells at lag phase of growth after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells at lag phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| MCF7 | IC50 |
23.3 μM
Compound: 7
|
Cytotoxicity against human MCF7 cells at lag phase of growth after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells at lag phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| MCF7 | IC50 |
41.1 μM
Compound: 7
|
Cytotoxicity against human sMCF7 cells at exponential phase of growth after 48 hrs by MTT assay
Cytotoxicity against human sMCF7 cells at exponential phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| Vero | IC50 |
33.9 μM
Compound: 7
|
Cytotoxicity against african green monkey Vero cells at exponential phase of growth after 48 hrs by MTT assay
Cytotoxicity against african green monkey Vero cells at exponential phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| Vero | IC50 |
36.7 μM
Compound: 7
|
Cytotoxicity against african green monkey Vero cells at lag phase of growth after 48 hrs by MTT assay
Cytotoxicity against african green monkey Vero cells at lag phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
化学情報
-
CAS 番号 24703-38-6
-
性状 Solid
-
分子量 360.44
-
分子式 C21H28O5
-
SMILES
O=C1[C@]23[C@@](C(C)(CCC3)C)([H])[C@@H]([C@@H](C4=CC(C(C)C)=C(O)C(O)=C42)OC)O1.[Rotation (-)]
-
別名
(-)-7-O-Methoxyrosmanol
-
Structure Classification
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)