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製品番号: HY-183885

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MPI3

MPI3 is a reversible covalent SARS-CoV-2 M_Pro inhibitor with an enzymatic IC₅₀ of 8.5 nM. MPI3 can be used for the research of covid-19.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 890648-84-7
分子式: C₂₆H₃₈N₄O₆
分子量:502.60

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

MPI3 構造式

CAS 番号: 890648-84-7

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

MPI3 is a reversible covalent SARS-CoV-2 M_Pro inhibitor with an enzymatic IC₅₀ of 8.5 nM. MPI3 can be used for the research of covid-19^[1].

体外実験

MPI3 potently inhibits purified SARS-CoV-2 M_Pro with an enzymatic IC₅₀ of 0.0085 μM^[1].
MPI3 (72 h) shows weak cellular inhibition of SARS-CoV-2 M_Pro in transiently transfected HEK293T/17 cells, with a cellular IC₅₀ greater than 2 μM^[1].
MPI3 weakly inhibits SARS-CoV-2 replication in Vero E6 cells, with an antiviral EC₅₀ greater than 5 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

化学情報

CAS 番号 890648-84-7
分子量 502.60
分子式 C₂₆H₃₈N₄O₆
SMILES

O=C(NCC1)[C@@H]1C[C@@H](C=O)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Cao W, et al. Evaluation of SARS-CoV-2 Main Protease Inhibitors Using a Novel Cell-Based Assay. ACS Cent Sci. 2022 Feb 23;8(2):192-204. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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