MTDB-Alkyne
MTDB-Alkyne (MTDB-Alk) is a β-coronavirus pseudoknot RNA-binding ligand that binds to the β-coronavirus pseudoknot RNA structure on the SARS-CoV-2 genome. MTDB-Alkyne can be used to synthesize Proximity-Induced Nucleic Acid Degrader (PINAD) for degrading SARS-CoV-2 RNA. MTDB-Alkyne is applicable to research related to the development of SARS-CoV-2-targeted RNA probes.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2923694-73-7
- 分子式: C21H25N5O2S
- 分子量:411.52
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
MTDB-Alkyne (MTDB-Alk) binds to the betacoronavirus pseudoknot RNA structure on the SARS‑CoV‑2 genome, and has no intrinsic RNA degrading activity; it can also be conjugated via CuAAC click chemistry to generate the PINAD-class molecule MTDB‑imi6[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2923694-73-7
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分子量 411.52
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分子式 C21H25N5O2S
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SMILES
O=C(C1=C(NC(N2CCN(CCC2)CC3=CSC(C)=N3)=O)C=CC=C1)NCC#C
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別名
MTDB-Alk
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)