N-Nitrosomorpholine-d8
Based on 1 Customer Validation
N-Nitrosomorpholine-d8 is deuterium labeled N-Nitrosomorpholine. N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.74%
- CAS 番号: 1219805-76-1
- 分子式: C4D8N2O2
- 分子量:124.17
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 1219805-76-1
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非標識Cas 59-89-2
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性状 Liquid
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分子量 124.17
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分子式 C4D8N2O2
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Color Colorless to light yellow
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SMILES
O=NN1C([2H])([2H])C([2H])([2H])OC([2H])([2H])C1([2H])[2H]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (805.35 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. K D Brunnemann, et al. N-Nitrosomorpholine and Other Volatile N-nitrosamines in Snuff Tobacco. Carcinogenesis. 1982;3(6):693-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.0535 mL | 40.2674 mL | 80.5348 mL | 201.3369 mL |
| 5 mM | 1.6107 mL | 8.0535 mL | 16.1070 mL | 40.2674 mL | |
| 10 mM | 0.8053 mL | 4.0267 mL | 8.0535 mL | 20.1337 mL | |
| 15 mM | 0.5369 mL | 2.6845 mL | 5.3690 mL | 13.4225 mL | |
| 20 mM | 0.4027 mL | 2.0134 mL | 4.0267 mL | 10.0668 mL | |
| 25 mM | 0.3221 mL | 1.6107 mL | 3.2214 mL | 8.0535 mL | |
| 30 mM | 0.2684 mL | 1.3422 mL | 2.6845 mL | 6.7112 mL | |
| 40 mM | 0.2013 mL | 1.0067 mL | 2.0134 mL | 5.0334 mL | |
| 50 mM | 0.1611 mL | 0.8053 mL | 1.6107 mL | 4.0267 mL | |
| 60 mM | 0.1342 mL | 0.6711 mL | 1.3422 mL | 3.3556 mL | |
| 80 mM | 0.1007 mL | 0.5033 mL | 1.0067 mL | 2.5167 mL | |
| 100 mM | 0.0805 mL | 0.4027 mL | 0.8053 mL | 2.0134 mL |
N-Nitrosomorpholine-d8 関連分類
HY-131123S1 関連分類
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