Oleoside dimethylester
Oleoside dimethylester is a secoiridoid glucoside found in the fruits of Ligustrum lucidum. Oleoside dimethylester exhibits inhibitory activity against type 3 parainfluenza virus (Para 3) and respiratory syncytial virus (RSV), with IC50 values of 20.8 and 83.2 μg/mL. Oleoside dimethylester also shows antioxidant effect.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 30164-95-5
- 分子式: C18H26O11
- 分子量:418.39
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
>80 μM
Compound: 10
|
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess reagent-based assay
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess reagent-based assay
|
[PMID: 32936639] |
| SK-BR-3 | IC50 |
>15 μM
Compound: 18
|
Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT reduction assay
Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT reduction assay
|
[PMID: 28551177] |
化学情報
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CAS 番号 30164-95-5
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分子量 418.39
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分子式 C18H26O11
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SMILES
COC(C[C@H]1/C([C@@H](OC=C1C(OC)=O)O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)=C\C)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)