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Omburtamab

(別名: Mab 8H9)
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Based on 1 Customer Validation

Omburtamab (Mab 8H9) is a mouse monoclonal immunoglobulin G1 (IgG1) antibody targeting B7-H3. Omburtamab specifically binds to the glycoprotein antigen B7-H3, which is widely expressed on the surface of tumor cells. As a targeting carrier for recombinant toxins, it delivers PE38 to inhibit cellular protein synthesis and induce cytotoxicity in antigen-expressing cancer cells. Omburtamab can be used in research related to glioma, breast cancer, osteosarcoma and neuroblastoma.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度 : 99.16%
  • CAS 番号: 1895083-75-6
  • 分子量:144.98 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Omburtamab
  • Experimental Validation Results for Omburtamab
  • Experimental Validation Results for Omburtamab
  • Omburtamab Chemical Structure
    Omburtamab 構造式
CAS 番号: 1895083-75-6
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Immobilized CD276/B7-H3 Protein, Human (433a.a, HEK293, His, HY-P70652) can bind Omburtamab. The EC50 for this effect is 45.43 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5×106 THP-1 cells with Omburtamab (HY-P99157, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Omburtamab Chemical Structure
    1/16
  • Omburtamab
  • Immobilized CD276/B7-H3 Protein, Human (433a.a, HEK293, His, HY-P70652) can bind Omburtamab. The EC50 for this effect is 45.43 ng/mL.
  • Flow cytometric analysis of 1.5×106 THP-1 cells with Omburtamab (HY-P99157, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • IgG1-kappa