PF-07293893
Based on 1 Customer Validation
PF-07293893 is an AMPKγ3 activator. PF-07293893 increases glycogen content, improves lipid oxidation, enhances mitochondrial biogenesis and promotes vascular repair. PF-07293893 is applicable to research related to heart failure.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.96%
- CAS 番号: 3036759-47-1
- 分子式: C26H23ClF4N6O2
- 分子量:562.95
-
保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
AMPK アイソフォーム固有の製品をすべて表示
More
生物活性
PF-07293893 selectively activates the γ3 subunit, which can increase glycogen content and lipid oxidation, improve mitochondrial biosynthesis, and promote vascular repair[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
-
CAS 番号 3036759-47-1
-
性状 Solid
-
分子量 562.95
-
分子式 C26H23ClF4N6O2
-
Color White to off-white
-
SMILES
CN1C=C(C(N2C[C@](C3=CC=CC(Cl)=C3F)(C4=C(C(NC5CN(C5)C([C@@H]6C[C@@H]6F)=O)=NC=C4C2=O)F)C)=N1)F
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 100 mg/mL (177.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (272 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7764 mL | 8.8818 mL | 17.7636 mL | 44.4089 mL |
| 5 mM | 0.3553 mL | 1.7764 mL | 3.5527 mL | 8.8818 mL | |
| 10 mM | 0.1776 mL | 0.8882 mL | 1.7764 mL | 4.4409 mL | |
| 15 mM | 0.1184 mL | 0.5921 mL | 1.1842 mL | 2.9606 mL | |
| 20 mM | 0.0888 mL | 0.4441 mL | 0.8882 mL | 2.2204 mL | |
| 25 mM | 0.0711 mL | 0.3553 mL | 0.7105 mL | 1.7764 mL | |
| 30 mM | 0.0592 mL | 0.2961 mL | 0.5921 mL | 1.4803 mL | |
| 40 mM | 0.0444 mL | 0.2220 mL | 0.4441 mL | 1.1102 mL | |
| 50 mM | 0.0355 mL | 0.1776 mL | 0.3553 mL | 0.8882 mL | |
| 60 mM | 0.0296 mL | 0.1480 mL | 0.2961 mL | 0.7401 mL | |
| 80 mM | 0.0222 mL | 0.1110 mL | 0.2220 mL | 0.5551 mL | |
| 100 mM | 0.0178 mL | 0.0888 mL | 0.1776 mL | 0.4441 mL |
PF-07293893 関連分類
HY-175747 関連分類
Powered by Bioz