PhAc-ALGP-Dox
PhAc-ALGP-Dox, a peptide-drug conjugate, is a novel anticancer prodrug, with IC50 values ranged from 311 nM to 34.25 μM for TNBC (E0771), normal murine epithelium (HC-11), human TNBC (MDA-MB-231 and MDA-MB-468), human CrC (LS 174T), normal human epithelium (HME-1) cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1616592-31-4
- 分子式: C45H58N5O19P
- 分子量:1003.94
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
PhAc-ALGP-Dox is sequentially activated via a tumor-specific two-step cleavage, initiated by extracellular THOP1 and further processed by FAPα/DPP4[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1616592-31-4
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分子量 1003.94
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分子式 C45H58N5O19P
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配列
{Phosphonoacetyl}-Ala-Leu-Gly-Pro-{Dox}
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シーケンスの短縮
{Phosphonoacetyl}-ALGP-{Dox}
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
PhAc-ALGP-Dox 関連分類
HY-P10760 関連分類
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