Prolylserine
Prolylserine, a dipeptide, is an inhibitor of melanogenesis production in Mel-Ab cells. Prolylserine decreases expression of microphthalmia-associated transcription factor (MITF) and tyrosinase, induces phorphosylation of ERK, but not cAMP response element binding protein (CREB).
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- CAS 番号: 71835-80-8
- 分子式: C8H14N2O4
- 分子量:202.21
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDCK | EC50 |
1.6 mM
Compound: 64
|
Activation of human PEPT1 expressed in MDCK cells
Activation of human PEPT1 expressed in MDCK cells
|
[PMID: 16759105] |
| MDCK | IC50 |
>16 mM
Compound: 64
|
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
|
[PMID: 16759105] |
化学情報
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CAS 番号 71835-80-8
-
分子量 202.21
-
分子式 C8H14N2O4
-
配列
H-Pro-Ser-OH
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シーケンスの短縮
PS
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)