CD1e
null CD1e is the most recently evolved member of the human CD1 lipid-antigen family and differs fundamentally from its cell-surface relatives. Synthesized as a membrane-bound β2-microglobulin-associated molecule, it is retained in endosomal compartments, where proteolytic cleavage releases a soluble form rather than delivering the protein to the plasma membrane. Soluble CD1e acts as a lipid-transfer and lipid-editing cofactor that hands glycolipid substrates to CD1b and CD1c for subsequent T-cell recognition. This helper function enables presentation of mycobacterial phosphatidyl-myo-inositol mannosides and positions CD1e as a unique intracellular stage of lipid antigen processing.
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CD1e 組換えタンパク質 (1)
- 生物種:
- 由来:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 分子式: Human
- 分子量: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
