R-87366
R-87366 is a water-soluble human immunodeficiency virus (HIV) protease inhibitor. R-87366 has potent inhibitory for HIV protease with a Ki value of 11 nM. R-87366 can be used for the research of anti-human immunodeficiency virus (HIV).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 144779-91-9
- 分子式: C32H39N7O6
- 分子量:617.70
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Ki: 11 nM (HIV protease)[1].
IC90: 0.5 μM (HIV-1IIIB acutely infected cells)[1]
R-87366 has potent inhibitory for human immunodeficiency virus protease with a Ki value of 11 nM[1].
R-87366 has activity for HIV-1IIIB acutely infected cells with an IC90 value of 0.5 μM[1].
R-87366 has moderate water-solubility[1].
R-87366 (0.25 μM; 0.5 μM) also has active in chronically infected Molt-4/HIV-1IIIB cells, and inhibits the proteolytic processing of p55 into p17[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 144779-91-9
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分子量 617.70
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分子式 C32H39N7O6
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SMILES
O=C(N(CCC1)[C@@H]1C(NC(C)(C)C)=O)[C@@H](O)[C@@H](NC([C@H](CC(N)=O)NC(C2=CN=C3C(C=CC=C3)=N2)=O)=O)CC4=CC=CC=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
R-87366 関連分類
HY-19232 関連分類
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