Ramelteon-d3
Based on 1 Customer Validation
Ramelteon-d3 (TAK-375-d3) is a deuterium-labelled Ramelteon (HY-A0014). Ramelteon is a potent, highly selective, and orally active agonist of MT1/MT2 with Ki values of 14 and 112 pM, respectively. Ramelteon has the potential for the research of insomnia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.0%
- CAS 番号: 1432057-38-9
- 分子式: C16H18D3NO2
- 分子量:262.36
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
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Help & FAQs
生物活性
製品説明
体外実験
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 1432057-38-9
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非標識Cas 196597-26-9
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性状 Solid
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分子量 262.36
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分子式 C16H18D3NO2
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Color White to off-white
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SMILES
[2H]C([2H])([2H])CC(NCC[C@H]1C2=C(CC1)C=CC3=C2CCO3)=O
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別名
TAK-375-d3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : ≥ 50 mg/mL (190.58 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (246 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8116 mL | 19.0578 mL | 38.1156 mL | 95.2889 mL |
| 5 mM | 0.7623 mL | 3.8116 mL | 7.6231 mL | 19.0578 mL | |
| 10 mM | 0.3812 mL | 1.9058 mL | 3.8116 mL | 9.5289 mL | |
| 15 mM | 0.2541 mL | 1.2705 mL | 2.5410 mL | 6.3526 mL | |
| 20 mM | 0.1906 mL | 0.9529 mL | 1.9058 mL | 4.7644 mL | |
| 25 mM | 0.1525 mL | 0.7623 mL | 1.5246 mL | 3.8116 mL | |
| 30 mM | 0.1271 mL | 0.6353 mL | 1.2705 mL | 3.1763 mL | |
| 40 mM | 0.0953 mL | 0.4764 mL | 0.9529 mL | 2.3822 mL | |
| 50 mM | 0.0762 mL | 0.3812 mL | 0.7623 mL | 1.9058 mL | |
| 60 mM | 0.0635 mL | 0.3176 mL | 0.6353 mL | 1.5881 mL | |
| 80 mM | 0.0476 mL | 0.2382 mL | 0.4764 mL | 1.1911 mL | |
| 100 mM | 0.0381 mL | 0.1906 mL | 0.3812 mL | 0.9529 mL |
Ramelteon-d3 関連分類
HY-A0014S1 関連分類
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