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製品番号: HY-P1044

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Spinorphin

(別名: LVV-hemorphin-4)

Spinorphin is an inhibitor of enkephalin-degrading enzymes. Spinorphin inhibits aminopeptidase, dipeptidyl aminopeptidase III, angiotensin-converting enzyme and enkephalinase. Spinorphin possesses an antinociceptive effect.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 137201-62-8
分子式: C₄₅H₆₄N₈O₁₀
分子量:877.04

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Spinorphin 構造式

CAS 番号: 137201-62-8

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数量

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
Oocyte	IC₅₀	48.1 pM Compound: 5, spinorphin	Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current in presence of 20 nM LVVYPWA peptide by two electrode voltage clamping technique Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current in presence of 20 nM LVVYPWA peptide by two electrode voltage clamping technique	[PMID: 17676725]
Oocyte	IC₅₀	8.3 pM Compound: 5, spinorphin	Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage clamping technique Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage clamping technique	[PMID: 17676725]

化学情報

CAS 番号 137201-62-8
分子量 877.04
分子式 C₄₅H₆₄N₈O₁₀
SMILES

C[C@@H](O)[C@@H](C(O)=O)NC([C@H](CC1=CNC2=CC=CC=C12)NC([C@H]3N(C([C@H](CC4=CC=C(C=C4)O)NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H](CC(C)C)N)=O)=O)=O)=O)CCC3)=O)=O
別名

LVV-hemorphin-4
配列

Leu-Val-Val-Tyr-Pro-Trp-Thr
シーケンスの短縮

LVVYPWT
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (276 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. M Honda, et al. Spinorphin, an endogenous inhibitor of enkephalin-degrading enzymes, potentiates leu-enkephalin-induced anti-allodynic and antinociceptive effects in mice. Jpn J Pharmacol. 2001 Dec;87(4):261-7. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

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濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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