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製品番号: HY-131502

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Taspine

Taspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 602-07-3
分子式: C₂₀H₁₉NO₆
分子量:369.37

保管条件:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Taspine 構造式

CAS 番号: 602-07-3

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

P2X Receptor アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
A-431	IC₅₀	11.2 μM Compound: 1	Antiproliferative activity against human A431 cells abnormally expressing EGFR after 48 hrs by MTT assay Antiproliferative activity against human A431 cells abnormally expressing EGFR after 48 hrs by MTT assay	[PMID: 20304537]
A549	IC₅₀	4.18 μM Compound: 1	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 20304537]
A549	IC₅₀	4.18 nM Compound: 1	Antiproliferative activity against human A549 cells Antiproliferative activity against human A549 cells	[PMID: 20006929]
Caco-2	IC₅₀	153 μM Compound: 1	Antiproliferative activity against human Caco-2 cells after 48 hrs by MTT assay Antiproliferative activity against human Caco-2 cells after 48 hrs by MTT assay	[PMID: 20304537]
Caco-2	IC₅₀	153 nM Compound: 1	Antiproliferative activity against human Caco-2 cells Antiproliferative activity against human Caco-2 cells	[PMID: 20006929]
ECV-304	IC₅₀	22.3 μM Compound: 1	Antiproliferative activity against human ECV304 cells after 48 hrs by MTT assay Antiproliferative activity against human ECV304 cells after 48 hrs by MTT assay	[PMID: 20304537]
ECV-304	IC₅₀	22.3 nM Compound: 1	Antiproliferative activity against human ECV304 cells Antiproliferative activity against human ECV304 cells	[PMID: 20006929]
HEK293	IC₅₀	15.95 μM Compound: 1	Antiproliferative activity against human HEK293 cells overexpressing EGFR after 48 hrs by MTT assay Antiproliferative activity against human HEK293 cells overexpressing EGFR after 48 hrs by MTT assay	[PMID: 20304537]

化学情報

CAS 番号 602-07-3
性状 Solid
分子量 369.37
分子式 C₂₀H₁₉NO₆
Color White to off-white
SMILES

O=C1C2=CC=C(OC)C(O3)=C2C4=C(C3=O)C(CCN(C)C)=CC(OC)=C4O1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (270 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Izzuddin Bin Nadzirin, et al. Taspine is a natural product that suppresses P2X4 receptor activity via phosphoinositide 3-kinase inhibition. Br J Pharmacol. 2021 Dec;178(24):4859-4872. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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生物活性
- 製品説明
化学情報
純度とドキュメンテーション
参考文献

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Taspine

P2X Receptor アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Taspine 関連分類

HY-131502 関連分類