Tedixaban
Tedixaban (Tedixabanum) is a Factor Xa inhibitor and anticoagulant with an IC50 of 0.50 nM. Tedixaban is applicable to research on thrombosis-related complications.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1333126-80-9
- 分子式: C23H22ClN5O2
- 分子量:435.91
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Tedixaban (DD217) is a small-molecule compound belonging to the class of coagulation factor Xa inhibitors. It has an in vitro IC50 of 0.50 nM, exhibits tight-binding characteristics, and acts as a competitive binding ligand, with an MM/GBSA total binding free energy of -46.9 kcal/mol[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
化学情報
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CAS 番号 1333126-80-9
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分子量 435.91
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分子式 C23H22ClN5O2
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SMILES
O=C(C1=CC=C(N(C)C(C)=N)C=C1)NC2=CC=C(C)C=C2C(NC3=NC=C(C=C3)Cl)=O
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別名
Tedixabanum
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)