Tilpisertib
Based on 1 Customer Validation
Tilpisertib (GS-4875) is a serine/threonine kinase inhibitor (WO2017007689).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.27%
- CAS 番号: 2065153-41-3
- 分子式: C33H33ClN8O
- 分子量:593.12
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
serine/threonine kinase[1]
Tilpisertib is a serine/threonine kinase inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 2065153-41-3
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性状 Solid
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分子量 593.12
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分子式 C33H33ClN8O
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Color Light yellow to yellow
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SMILES
O=C1C2=CC=CC([C@@H](C3=CN(N=N3)C4(C5)CC5C4)NC6=CC(C(NCC(C)(C)C)=C7C#N)=C(N=C7)C(Cl)=C6)=C2C=CN1C
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別名
GS-4875
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (210.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. WO2017007689
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6860 mL | 8.4300 mL | 16.8600 mL | 42.1500 mL |
| 5 mM | 0.3372 mL | 1.6860 mL | 3.3720 mL | 8.4300 mL | |
| 10 mM | 0.1686 mL | 0.8430 mL | 1.6860 mL | 4.2150 mL | |
| 15 mM | 0.1124 mL | 0.5620 mL | 1.1240 mL | 2.8100 mL | |
| 20 mM | 0.0843 mL | 0.4215 mL | 0.8430 mL | 2.1075 mL | |
| 25 mM | 0.0674 mL | 0.3372 mL | 0.6744 mL | 1.6860 mL | |
| 30 mM | 0.0562 mL | 0.2810 mL | 0.5620 mL | 1.4050 mL | |
| 40 mM | 0.0421 mL | 0.2107 mL | 0.4215 mL | 1.0537 mL | |
| 50 mM | 0.0337 mL | 0.1686 mL | 0.3372 mL | 0.8430 mL | |
| 60 mM | 0.0281 mL | 0.1405 mL | 0.2810 mL | 0.7025 mL | |
| 80 mM | 0.0211 mL | 0.1054 mL | 0.2107 mL | 0.5269 mL | |
| 100 mM | 0.0169 mL | 0.0843 mL | 0.1686 mL | 0.4215 mL |
Tilpisertib 関連分類
HY-137456 関連分類
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