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製品番号: HY-N10082

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Trigoxyphin A

Trigoxyphin A is a oxygenated daphnane-type diterpenoids. Trigoxyphin A exhibites strong cytotoxic activity against HL60 and A549 with IC₅₀s of 0.27 and 7.5 μM, respectively.

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CAS 番号: 1236874-00-2
分子式: C₃₄H₃₄O₉
分子量:586.63

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (281 KB)

Trigoxyphin A 構造式

CAS 番号: 1236874-00-2

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生物活性

製品説明

Trigoxyphin A is a oxygenated daphnane-type diterpenoids. Trigoxyphin A exhibites strong cytotoxic activity against HL60 and A549 with IC₅₀s of 0.27 and 7.5 μM, respectively^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>10 μM Compound: 8	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay	[PMID: 21192108]
A549	IC₅₀	7.5 μM Compound: 1	Cytotoxicity against human A549 cells after 72 hrs by SRB assay Cytotoxicity against human A549 cells after 72 hrs by SRB assay	[PMID: 20593838]
Bel-7402	IC₅₀	>10 μM Compound: 1	Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay	[PMID: 20593838]
HL-60	IC₅₀	>10 μM Compound: 8	Cytotoxicity against human HL60 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HL60 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 21192108]
HL-60	IC₅₀	0.27 μM Compound: 1	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 20593838]
MCF7	IC₅₀	>10 μM Compound: 8	Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay	[PMID: 21192108]

化学情報

CAS 番号 1236874-00-2
分子量 586.63
分子式 C₃₄H₃₄O₉
SMILES

C[C@H]1[C@]23[C@]([C@H]4[C@](O4)([C@H]([C@]5([C@@]3([H])C=C(C5=O)C)O)O)C)([H])[C@]6([H])[C@]([C@H]1OC(C7=CC=CC=C7)=O)(O[C@](O6)(C8=CC=CC=C8)O2)C(C)=C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (281 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Lin BD, et al. Trigoxyphins A-G: diterpenes from Trigonostemon xyphophylloides. J Nat Prod. 2010 Jul 23;73(7):1301-5. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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