country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-N21698

Copy Link Print Information

Uralodin B

Uralodin B is a naturally occurring polycyclic polyprenylated acylphloroglucinol (PPAP) and is the C (30)-epimer of Uralodin C. It is found in the aerial parts of Hypericum henryi subsp. uraloides. Uralodin B exhibits cytotoxic activity against SGC7901 and HL-60 tumor cells. It is useful for research related to PPAP natural products and tumor cytotoxicity.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1253206-38-0
分子式: C₃₈H₅₀O₅
分子量:586.80

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (288 KB)

Uralodin B 構造式

CAS 番号: 1253206-38-0

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Endogenous Metabolite アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC50	21.8 μM	Cytotoxic activity against human HL-60 promyelocytic leukemia cells assessed by MTT assay after 48 h of continuous exposure. Cytotoxic activity against human HL-60 promyelocytic leukemia cells assessed by MTT assay after 48 h of continuous exposure.	20087990
SGC-7901	IC50	63.7 μM	Cytotoxic activity against human SGC7901 gastric carcinoma cells assessed by MTT assay after 48 h of continuous exposure. Cytotoxic activity against human SGC7901 gastric carcinoma cells assessed by MTT assay after 48 h of continuous exposure.	20087990
HepG2	IC50	171.0 μM	Cytotoxic activity against human HepG2 hepatocellular carcinoma cells assessed by MTT assay after 48 h of continuous exposure. Cytotoxic activity against human HepG2 hepatocellular carcinoma cells assessed by MTT assay after 48 h of continuous exposure.	20087990
K562	IC50	171.0 μM	Cytotoxic activity against human K562 chronic myelogenous leukemia cells assessed by MTT assay after 48 h of continuous exposure. Cytotoxic activity against human K562 chronic myelogenous leukemia cells assessed by MTT assay after 48 h of continuous exposure.	20087990

体外実験

Anti-cancer

Uralodin B (0.064-40 μM; 48 h) exerts modest cytotoxic effects against HL-60 and SGC7901 cells with IC₅₀ values of 21.8 μM and 63.7 μM, respectively, while showing weak activity against HepG2 and K562 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

HepG2 human hepatocellular carcinoma cells, SGC7901 human gastric carcinoma cells, HL-60 human promyelocytic leukemia cells, K562 human chronic myelogenous leukemia cells
Concentration:

0.064, 0.32, 1.6, 8, 40 μM
Incubation Time:

48 h
Result:

Exhibited the most potent cytotoxic activity against HL-60 cells, with an IC50 of 21.8 μM.
Showed modest cytotoxicity against SGC7901 cells, with an IC50 of 63.7 μM.
Showed minimal cytotoxic activity against HepG2 and K562 cell lines, with IC50 values of 171.0 μM for both cell lines.

Related Protocols :

化学情報

CAS 番号 1253206-38-0
分子量 586.80
分子式 C₃₈H₅₀O₅
SMILES

O=C(C1=CC=CC=C1)[C@@]23[C@@](C)([C@H](C[C@@](C2=O)(C4=C(C[C@@H](O4)C(C)(O)C)C3=O)C/C=C(C)\C)C/C=C(C)\C)CC/C=C(C)/C
Structure Classification
- Terpenoids
- Other Monoterpenes
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (288 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Chen XQ, et al. Polycyclic polyprenylated acylphloroglucinols and chromone O-glucosides from Hypericum henryi subsp. uraloides. Chemistry & biodiversity. 2010 Jan;7(1):196-204.

[2]. Hu JW, et al. Methylated Polycyclic Polyprenylated Acylphloroglucinol Derivatives from Hypericum ascyron. Journal of natural products. 2018 Nov 26;81(11):2348-2356.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ