WAY-658674
Based on 1 Customer Validation
WAY-658674 is an active molecule for the study of amyloid diseases and synucleinopathies.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.0%
- CAS 番号: 42310-54-3
- 分子式: C12H13ClN2O2S
- 分子量:284.77
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
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Help & FAQs
生物活性
製品説明
化学情報
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CAS 番号 42310-54-3
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性状 Solid
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分子量 284.77
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分子式 C12H13ClN2O2S
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Color White to off-white
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SMILES
CC1=C(C=CC(Cl)=C1)OCC(NC2=NCCS2)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (175.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Amyloid: Congo Red Amyloid Staining
Congo red amyloid staining is a histochemical method used to detect extracellular amyloid deposits in tissue sections based on the affinity of Congo red dye for β-pleated sheet-rich protein aggregates. When bound to amyloid, Congo red produces characteristic apple-green birefringence under polarized light microscopy, which is widely regarded as a diagnostic feature of amyloid deposition in histopathology. The diagnostic principle relies on the combination of dye binding (congophilia) and optical anisotropy under polarized illumination, which distinguishes amyloid from most non-amyloid eosinophilic extracellular deposits in routine histological evaluation. Amyloid identification by Congo red staining remains a cornerstone in diagnostic pathology despite the availability of adjunct methods such as immunohistochemistry and mass spectrometry, particularly because of its ability to localize deposits directly within tissue architecture. The specificity of Congo red-positive deposits is incre
純度とドキュメンテーション
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データシート (241 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5116 mL | 17.5582 mL | 35.1163 mL | 87.7908 mL |
| 5 mM | 0.7023 mL | 3.5116 mL | 7.0233 mL | 17.5582 mL | |
| 10 mM | 0.3512 mL | 1.7558 mL | 3.5116 mL | 8.7791 mL | |
| 15 mM | 0.2341 mL | 1.1705 mL | 2.3411 mL | 5.8527 mL | |
| 20 mM | 0.1756 mL | 0.8779 mL | 1.7558 mL | 4.3895 mL | |
| 25 mM | 0.1405 mL | 0.7023 mL | 1.4047 mL | 3.5116 mL | |
| 30 mM | 0.1171 mL | 0.5853 mL | 1.1705 mL | 2.9264 mL | |
| 40 mM | 0.0878 mL | 0.4390 mL | 0.8779 mL | 2.1948 mL | |
| 50 mM | 0.0702 mL | 0.3512 mL | 0.7023 mL | 1.7558 mL | |
| 60 mM | 0.0585 mL | 0.2926 mL | 0.5853 mL | 1.4632 mL | |
| 80 mM | 0.0439 mL | 0.2195 mL | 0.4390 mL | 1.0974 mL | |
| 100 mM | 0.0351 mL | 0.1756 mL | 0.3512 mL | 0.8779 mL |
WAY-658674 関連分類
HY-W674257 関連分類
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