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WEE1-IN-14

WEE1-IN-14 (Compound 14) is a selective WEE1 inhibitor (IC50: 0.5 nM in L-RB-FEP calculations, 1.0 nM in ADP-Glo kinase assay). Inhibition of Wee1 in cancer cells disrupts the G2-M checkpoint, removes the regulatory controls on the cell cycle, and leads to early onset of mitotic failure followed by apoptosis of tumor cells. Therefore, WEE1-IN-14 is a useful tool for studying cancer biology.

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  • CAS 番号: 2803921-87-9
  • 分子式: C25H25Cl2N7O
  • 分子量:510.42
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • WEE1-IN-14 Chemical Structure
    WEE1-IN-14 構造式
CAS 番号: 2803921-87-9
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  • WEE1-IN-14 Chemical Structure
    WEE1-IN-14 Chemical Structure
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  • WEE1-IN-14