Zapalog
Based on 1 publication(s) in Google Scholar
Zapalog is a photocleavable small-molecule heterodimerizer that can be used to repeatedly initiate, and instantaneously terminate, a physical interaction between two target proteins. Zapalog dimerizes any two proteins tagged with the FKBP and DHFR domains until exposure to light causes its photolysis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.62%
- CAS 番号: 1708091-24-0
- 分子式: C58H73N7O15
- 分子量:1108.24
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
MedChemExpress(MCE)の使用を引用している文献 Zapalog
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生物活性
FKBP, DHFR[1]
化学情報
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CAS 番号 1708091-24-0
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性状 Solid
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分子量 1108.24
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分子式 C58H73N7O15
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Color White to yellow
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SMILES
O=C([C@H]1N(C(C(C(C)(C)CC)=O)=O)CCCC1)O[C@@H](C2=CC=CC(NC(CCCOC3=CC([N+]([O-])=O)=C(C(OCCOC4=C(OC)C=C(CC5=CN=C(N)N=C5N)C=C4OC)C)C=C3OC)=O)=C2)CCC6=CC=C(OC)C(OC)=C6
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
溶剤 & 溶解度
DMSO : 100 mg/mL (90.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9023 mL | 4.5117 mL | 9.0233 mL | 22.5583 mL |
| 5 mM | 0.1805 mL | 0.9023 mL | 1.8047 mL | 4.5117 mL | |
| 10 mM | 0.0902 mL | 0.4512 mL | 0.9023 mL | 2.2558 mL | |
| 15 mM | 0.0602 mL | 0.3008 mL | 0.6016 mL | 1.5039 mL | |
| 20 mM | 0.0451 mL | 0.2256 mL | 0.4512 mL | 1.1279 mL | |
| 25 mM | 0.0361 mL | 0.1805 mL | 0.3609 mL | 0.9023 mL | |
| 30 mM | 0.0301 mL | 0.1504 mL | 0.3008 mL | 0.7519 mL | |
| 40 mM | 0.0226 mL | 0.1128 mL | 0.2256 mL | 0.5640 mL | |
| 50 mM | 0.0180 mL | 0.0902 mL | 0.1805 mL | 0.4512 mL | |
| 60 mM | 0.0150 mL | 0.0752 mL | 0.1504 mL | 0.3760 mL | |
| 80 mM | 0.0113 mL | 0.0564 mL | 0.1128 mL | 0.2820 mL |