Zeripatamig
Based on 1 Customer Validation
Zeripatamig is an anti-CD19/CD47 human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: ≥99.0%
- CAS 番号: 2607644-43-7
- 分子量:143.846 kDa
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
IgG1-lambda-kappa
Human
CD19 & CD47
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
P11609 & Q61735-1
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-lambda-kappa
ELISA, FACS, Functional assay
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Flow cytometric analysis of 1X106 Raji cells with Zeripatamig (HY-P990694, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black). -
Flow cytometric analysis of 1X106 Jurkat cells with Zeripatamig (HY-P990694, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black). -
Loaded Zeripatamig on AHC2 biosensor, can bind CD47 Protein, Human (HEK293, His, HY-P7336) with an affinity constant of 1.692E-08 M as determined in BLI assay. -
Loaded Zeripatamig on AHC2 biosensor, can bind CD19 Protein, Human (HEK293, His, HY-P74330) with an affinity constant of 2.935E-09 M as determined in BLI assay.
化学情報
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CAS 番号 2607644-43-7
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性状 Liquid
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分子量 143.846 kDa
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Color Colorless to light yellow
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別名
TG-1801
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輸送条件
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (253 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
参考文献
[1]. Zeripatamig
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)