1. Metabolic Enzyme/Protease
  2. MAGL
  3. JW 618

JW 618 is a selective ABHD6 inhibitor, with IC50s of 38 and 13 nM for mouse and rat ABHD6.

For research use only. We do not sell to patients.

JW 618 Chemical Structure

JW 618 Chemical Structure

CAS No. : 1416133-88-4

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Description

JW 618 is a selective ABHD6 inhibitor, with IC50s of 38 and 13 nM for mouse and rat ABHD6[1].

In Vitro

JW 618 (0.1-50 μM, 30 min) inhibits protein expression of MAGL and ABHD6 in mouse or rat brain proteomes[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

392.30

Formula

C17H14F6N2O2

CAS No.
SMILES

O=C(N(CC1=CC(C2=CC=NC=C2)=CC=C1)C)OC(C(F)(F)F)C(F)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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JW 618 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
JW 618
Cat. No.:
HY-117722
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