1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. KCa2 channel modulator 2

KCa2 channel modulator 2 (compound 2q) is a potent subtype-selective positive modulator of KCa2 channel. KCa2 channel modulator 2 exhibits similar potency on the rat KCa2.2a and human KCa2.3 channel subtypes, with EC50s of 0.64 μM and 0.60 μM, respectively

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KCa2 channel modulator 2 Chemical Structure

KCa2 channel modulator 2 Chemical Structure

CAS No. : 2764618-34-8

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Description

KCa2 channel modulator 2 (compound 2q) is a potent subtype-selective positive modulator of KCa2 channel. KCa2 channel modulator 2 exhibits similar potency on the rat KCa2.2a and human KCa2.3 channel subtypes, with EC50s of 0.64 μM and 0.60 μM, respectively[1]

Molecular Weight

331.78

Formula

C16H15ClFN5

CAS No.
SMILES

CC1=CC(NC2=C(C=CC(Cl)=C2)F)=NC(N3C(C)=CC(C)=N3)=N1

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KCa2 channel modulator 2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KCa2 channel modulator 2
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HY-142735
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