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Cat. No.: HY-100570

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KF15766

KF15766 (compd 34E) is an orally active TXA₂ and H₁ dual antagonist with K_is of 740 and 20 nM. KF15766 can be used for antiallergic research.

For research use only. We do not sell to patients.

CAS No.: 124907-44-4
Formula: C₃₀H₃₁NO₃.1/2C₄H₄O₄
Molecular Weight:511.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

KF15766 Chemical Structure

CAS No.: 124907-44-4

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Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
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Help & FAQs
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Biological Activity

Description

KF15766 (compd 34E) is an orally active TXA₂ and H₁ dual antagonist with K_is of 740 and 20 nM. KF15766 can be used for antiallergic research^[1].

All Prostaglandin Receptor Isoforms :

In Vivo

KF15766 (0.3, 10 mg/kg, p.o.) prevents Histamine- and U-46619-induced bronchoconstrictions in guinea pigs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 124907-44-4
Molecular Weight 511.62
Formula C₃₀H₃₁NO₃.1/2C₄H₄O₄
SMILES

O=C(O)CC1=CC=C(C/2=C1)OCC3=CC=CC=C3C2=C/CN4CCC(CC5=CC=CC=C5)CC4.O=C(O)/C=C/C(O)=O.[1/2]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ohshima E, et al. Dibenz[b,e]oxepin derivatives: novel antiallergic agents possessing thromboxane A2 and histamine H1 dual antagonizing activity. 1. J Med Chem. 1993 Feb 5;36(3):417-20. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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- In Vivo
Chemical Information
Purity & Documentation
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KF15766

All Prostaglandin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

KF15766 Related Classifications

HY-100570 Related Classifications