Apoptosis inducer 36
Apoptosis inducer 36 (Compound 42) exhibits anti-leukemic activity through reduction of leukemia stem cells (LSCs) and induction of differentiation. Apoptosis inducer 36 inhibits the proliferation of AML cells, arrests cell cycle at G1 phase, and induces PANoptosis including apoptosis, pyroptosis and necrosis. Prodrug of apoptosis inducer 36 exhibits orally active antitumor efficacy in mouse model.
For research use only. We do not sell to patients.
- CAS No.: 2831492-41-0
- Formula: C23H40O3Si
- Molecular Weight:392.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2831492-41-0
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Molecular Weight 392.65
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Formula C23H40O3Si
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SMILES
[H][C@@]12CC(C(O[C@@H]1CC[C@@]3([C@H](CC[C@]32[H])O[Si](C(C)C)(C(C)C)C(C)C)C)=O)=C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)