B 746
B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin.
For research use only. We do not sell to patients.
- CAS No.: 103051-26-9
- Formula: C26H20Cl2N4
- Molecular Weight:459.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
B746 (1, 3, 10 μM; 7 days) significantly inhibits the growth of mycobacteria[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:beige mice
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Dosage:10, 20, 30 mg/kg
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Administration:p.o.; 10, 20, 30 mg/kg; single dose; first day and 2, 4 and 6 week after infection
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Result:Reduced Colony Forming Units (CFU) counts of Mycobacteria in spleen of beige mice.
Chemical Information
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CAS No. 103051-26-9
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Molecular Weight 459.37
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Formula C26H20Cl2N4
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SMILES
CC/N=C1C=C2N(C3=C(N=C2C=C\1NC4=CC=C(C=C4)Cl)C=CC=C3)C5=CC=C(C=C5)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
B 746 Related Classifications
HY-113729 Related Classifications
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