KR-12 (human)
Based on 1 Customer Validation
KR-12 (human) is an active segment of LL-37 (HY-P4744). KR-12 (human) exhibits antimicrobial activity against gram-negative bacteria. KR-12 (human) inhibits E. coli K-12 with a MIC of 66 μM. KR-12 human can be used for the research of infection, such as E. coli infection.
For research use only. We do not sell to patients.
- Purity: 99.91%
- CAS No.: 1218951-51-9
- Formula: C71H127N25O15
- Molecular Weight:1570.93
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
KR-12 (human) inhibits E. coli K-12 with a MIC of 66 μM[1].
KR-12 (human) is inactive against S. aureus UAMS-1 and USA300 with MIC values >264 μM[1].
KR-12 (human) (40 μM) shows Little or no leakage from E. coli cytoplasmic membranes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1218951-51-9
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Appearance Solid
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Molecular Weight 1570.93
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Formula C71H127N25O15
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Color White to off-white
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Sequence
Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2
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Sequence Shortening
KRIVQRIKDFLR-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 100 mg/mL (63.66 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.6366 mL | 3.1828 mL | 6.3657 mL | 15.9141 mL |
| 5 mM | 0.1273 mL | 0.6366 mL | 1.2731 mL | 3.1828 mL | |
| 10 mM | 0.0637 mL | 0.3183 mL | 0.6366 mL | 1.5914 mL | |
| 15 mM | 0.0424 mL | 0.2122 mL | 0.4244 mL | 1.0609 mL | |
| 20 mM | 0.0318 mL | 0.1591 mL | 0.3183 mL | 0.7957 mL | |
| 25 mM | 0.0255 mL | 0.1273 mL | 0.2546 mL | 0.6366 mL | |
| 30 mM | 0.0212 mL | 0.1061 mL | 0.2122 mL | 0.5305 mL | |
| 40 mM | 0.0159 mL | 0.0796 mL | 0.1591 mL | 0.3979 mL | |
| 50 mM | 0.0127 mL | 0.0637 mL | 0.1273 mL | 0.3183 mL | |
| 60 mM | 0.0106 mL | 0.0530 mL | 0.1061 mL | 0.2652 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
KR-12 (human) Related Classifications
HY-P10257 Related Classifications
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