2,5-DMBQ
Based on 1 Customer Validation
2,5-DMBQ (2,5-Dimethoxybenzoquinone) serves as an extracellular reductant. 2,5-DMBQ is involved in a crucial redox cycle, namely the extracellular hydroquinone-quinone redox cycle. In this cycle, 2,5-DMBQ is capable of reducing extracellular Fe³⁺ and generating H2O2. 2,5-DMBQ plays a pivotal role in the biodegradation mechanism of brown rot fungal, assisting the fungi in decomposing and utilizing organic matter.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.99%
- CAS No.: 3117-03-1
- 화학식: C8H8O4
- 분자량:168.15
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Cancer cell lines | ED50 |
1.3 μg/mL
Compound: 4
|
Cytotoxicity against human lung cancer cells
Cytotoxicity against human lung cancer cells
|
[PMID: 1965200] |
| Cancer cell lines | ED50 |
1.4 μg/mL
Compound: 4
|
Cytotoxicity against human colon cancer cells
Cytotoxicity against human colon cancer cells
|
[PMID: 1965200] |
| Cancer cell lines | ED50 |
5.2 μg/mL
Compound: 4
|
Cytotoxicity against human breast cancer cells
Cytotoxicity against human breast cancer cells
|
[PMID: 1965200] |
| HT-1080 | ED50 |
3.4 μg/mL
Compound: 4
|
Cytotoxicity against human HT1080 cells
Cytotoxicity against human HT1080 cells
|
[PMID: 1965200] |
| KB | ED50 |
3.8 μg/mL
Compound: 4
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 1965200] |
| Melanoma cell | ED50 |
2.7 μg/mL
Compound: 4
|
Cytotoxicity against human melanoma cells
Cytotoxicity against human melanoma cells
|
[PMID: 1965200] |
| P388 | ED50 |
2.5 μg/mL
Compound: 4
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 1965200] |
Chemical Information
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CAS No. 3117-03-1
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Appearance Solid
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분자량 168.15
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화학식 C8H8O4
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Color Light yellow to yellow
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SMILES
O=C1C(OC)=CC(C(OC)=C1)=O
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Synonyms
2,5-Dimethoxybenzoquinone
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
순도&문서
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Varela E, et al. Effect of pH and oxalate on hydroquinone-derived hydroxyl radical formation during brown rot wood degradation. Appl Environ Microbiol. 2003;69(10):6025-6031. [Content Brief]
[2]. Jensen KA Jr, et al. Pathways for extracellular Fenton chemistry in the brown rot basidiomycete Gloeophyllum trabeum. Appl Environ Microbiol. 2001 Jun;67(6):2705-11. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)