5(R)-HETE
5(R)-HETE is a lipoxygenase product of arachidonic acid. 5(R)-HETE is an inducer of neutrophil migration through endothelial and epithelial barriers. 5(R)-HETE is important in mediating lung inflammatory processes.
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- CAS No.: 61641-47-2
- 화학식: C20H32O3
- 분자량:320.47
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
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HY-113336B
(±)15-HETEPROTAC Linkers -
HY-124355
4-Hydroxy hexenalLipid Peroxidation Product -
HY-120954
14,15-EE-5(Z)-E14,15-EET structural analogue -
HY-150084
(±)14,15-Epoxyeicosatrienoic acidProliferation Inducer -
HY-113490
15-KETE -
HY-115421
11(R)-HEPEMonohydroxy Fatty Acid -
HY-130675A
15(S)-HEPEAsthma Marker -
HY-113434
5(S)-HETEEndogenous Metabolite -
HY-113884B
(S)-Coriolic acidPPARγ Activator/Mitochondrial Dysfunction Inducer -
HY-130309
(±)8(9)-EpETEEpoxide -
HY-124404A
12(S)-HETEP38 MAPK/ERK Activator -
HY-117044A
(±)12-HEPE
All Endogenous Metabolite Isoforms
More
Biological Activity
제품 설명
Chemical Information
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CAS No. 61641-47-2
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분자량 320.47
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화학식 C20H32O3
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SMILES
CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](O)CCCC(O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Phagocytosis Functional Assay
A phagocytosis functional assay measures the ability of phagocytic cells, such as neutrophils, macrophages, monocytes, or microglia/macrophages, to bind and internalize particulate targets including bacteria, yeast particles, beads, or myelin particles. Fluorescent flow-cytometry assays detect target uptake as fluorescence associated with gated phagocytes, while pH-sensitive dyes such as pHrodo increase signal in acidic phagosomal compartments and therefore preferentially report internalized particles rather than particles remaining outside the cell. Microscopy or high-content imaging can be used to confirm intracellular localization and, in some protocols, to follow uptake kinetics.
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Cell migration
Cell migration is a method that plays an important role in wound healing, cell differentiation, embryonic development, etc.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5(R)-HETE Related Classifications
HY-113434A Related Classifications
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