Hydroxycotinine
Based on 1 Customer Validation
Hydroxycotinine is a nicotine metabolite commonly found in the urine of smokers. Hydroxycotinine is the primary biomarker of tobacco/nicotine vapor exposure, formed from the conversion of nicotine via cotinine. Hydroxycotinine serum levels in rodents are influenced by sex and co-exposure to nicotine vapor and ethanol. Hydroxycotinine elevation is associated with decreased eGFR and increased risk of chronic kidney disease. Hydroxycotinine can be used in research related to chronic kidney disease.
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- Purity : 99.13%
- CAS No.: 34834-67-8
- 화학식: C10H12N2O2
- 분자량:192.22
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보관:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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HY-B1178
CotinineEndogenous Metabolite -
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Ethyl glucuronide-d5Stable Isotope -
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Cotinine (Standard)Endogenous Metabolite -
HY-D0958
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HY-W017464
NAPQIAcetaminophen Metabolite -
HY-160236
3-(3-Sulfooxyphenyl)propanoic acidMetabolite of Echinacoside -
HY-W016221
6-Hydroxy ChlorzoxazoneChlorzoxazone Metabolite -
HY-W009247
N-DesmethylolanzapineAntipsychotic Agent -
HY-114992
2-Propyl-2-pentenoic acidValproic Acid Metabolite -
HY-118774
Propofol β-D-glucuronideMetabolite -
HY-G0021S
N-Desmethylclozapine-d8Stable Isotope
Biological Activity
제품 설명
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 34834-67-8
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Appearance Solid
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분자량 192.22
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화학식 C10H12N2O2
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Color White to off-white
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SMILES
O=C1N(C)[C@H](C2=CC=CN=C2)C[C@H]1O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
용액&용해도
In Vitro:
DMSO : 30 mg/mL (156.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.2024 mL | 26.0119 mL | 52.0237 mL | 130.0593 mL |
| 5 mM | 1.0405 mL | 5.2024 mL | 10.4047 mL | 26.0119 mL | |
| 10 mM | 0.5202 mL | 2.6012 mL | 5.2024 mL | 13.0059 mL | |
| 15 mM | 0.3468 mL | 1.7341 mL | 3.4682 mL | 8.6706 mL | |
| 20 mM | 0.2601 mL | 1.3006 mL | 2.6012 mL | 6.5030 mL | |
| 25 mM | 0.2081 mL | 1.0405 mL | 2.0809 mL | 5.2024 mL | |
| 30 mM | 0.1734 mL | 0.8671 mL | 1.7341 mL | 4.3353 mL | |
| 40 mM | 0.1301 mL | 0.6503 mL | 1.3006 mL | 3.2515 mL | |
| 50 mM | 0.1040 mL | 0.5202 mL | 1.0405 mL | 2.6012 mL | |
| 60 mM | 0.0867 mL | 0.4335 mL | 0.8671 mL | 2.1677 mL | |
| 80 mM | 0.0650 mL | 0.3251 mL | 0.6503 mL | 1.6257 mL | |
| 100 mM | 0.0520 mL | 0.2601 mL | 0.5202 mL | 1.3006 mL |
Hydroxycotinine Related Classifications
HY-113239 Related Classifications
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