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Cat. No.: HY-100962A

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AG 99

(Synonyms: Tyrphostin 46; Tyrphostin AG 99)

1 Cited Publications

고객리뷰

Based on 1 publication(s) in Google Scholar

AG 99 (Tyrphostin 46), a tyrphostin derivative, is a tyrosine kinase inhibitor that increases sister chromatid exchange frequency in transformed CHO-K1 and primary CHE cells. AG 99 is promising for research of proliferative diseases.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 118409-59-9
화학식: C₁₀H₈N₂O₃
분자량:204.18

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

AG 99 Chemical Structure

CAS No.: 118409-59-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- Cellular Effect
Chemical Information
Publications (1)
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Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
A-431	IC₅₀	1 × 10 ¹μM Compound: 126	Inhibition of EGFR in human A431 cells Inhibition of EGFR in human A431 cells	[PMID: 1479375]

Chemical Information

CAS No. 118409-59-9
분자량 204.18
화학식 C₁₀H₈N₂O₃
SMILES

O=C(/C(C#N)=C/C1=CC=C(C(O)=C1)O)N
Synonyms

Tyrphostin 46; Tyrphostin AG 99
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Life Sci

Drug repurposing reveals Fmoc-l-leucine as an adipose thermogenesis activator in cold-exposed mice by targeting PPARγ/UCP1. [Abstract]

2026 Apr 1:390:124259. PMID: 41655780

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bassi L, et al. Clastogenic effects of two tyrosine kinase inhibitors, tyrphostin 23 and tyrphostin 46, on a transformed (CHO-K1) and on a primary embryonic chinese hamster cell line (CHE). Mutagenesis. 2000 Jul;15(4):341-7. [Content Brief]

[2]. Hubert EM, et al. Inhibition of volume-stimulated taurine efflux and tyrosine kinase activity in the skate red blood cell. Pflugers Arch. 2000 May;440(1):132-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

100 mg

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Biological Activity
- 제품 설명
Chemical Information
Publications (1)
순도&문서
References

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AG 99

Publications Citing Use of MedChemExpress (MCE) AG 99