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Cat. No.: HY-146059

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Antibacterial agent 99

Antibacterial agent 99 (compound 7b) is a potent antibacterial agent. Antibacterial agent 99 shows significant antibacterial and antifungal activity. Antibacterial agent 99 dose not show haemolytic activity.

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CAS No.: 2452306-13-5
화학식: C₂₇H₂₇BrN₂
분자량:459.42

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Antibacterial agent 99 Chemical Structure

CAS No.: 2452306-13-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	CC₅₀	2.1 μg/mL Compound: 7b	Cytotoxicity against HEK293 cells measured after 20 hrs by resazurin dye based fluorescence assay Cytotoxicity against HEK293 cells measured after 20 hrs by resazurin dye based fluorescence assay	[PMID: 32619924]

In Vitro

Antibacterial agent 99 (compound 7b) shows antimicrobial activity with MIC of 8, 8, 16 μg/mL for Sa - Staphylococcus aureus (MRSA) ATCC 43300, Ca - Candida albicansATCC 90028, Cn - Cryptococcus neoformans H99 ATCC 208821, respectively^[1].
Antibacterial agent 99 shows cytotoxicity with an CC₅₀ of 2.1 μg/mL for HEK293 cells, and haemolytic activity with an HC₁₀ of >32 μg/mL for human red blood cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2452306-13-5
분자량 459.42
화학식 C₂₇H₂₇BrN₂
SMILES

CC1=CC=C(C=C1)[N+]2=C3N(CCCCC3)C(C4=CC=C(C=C4)C5=CC=CC=C5)=C2.[Br-]
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Demchenko S, et al. Synthesis, antibacterial and antifungal activity of new 3-biphenyl-3H-Imidazo[1,2-a]azepin-1-ium bromides. Eur J Med Chem. 2020 Sep 1;201:112477. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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