Anticancer agent 182
Anticancer agent 182 (Compound 1) is a cytotoxic flavonoid compound isolated from the root ofMuntingia colabura L. Anticancer agent 182 exhibits anticancer activity.
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- CAS No.: 133342-90-2
- 화학식: C18H20O5
- 분자량:316.35
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BC1 cell line | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human BC1 cells
Cytotoxicity against human BC1 cells
|
[PMID: 2045815] |
| Col2 | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human Col2 cells
Cytotoxicity against human Col2 cells
|
[PMID: 2045815] |
| HT-1080 | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human HT1080 cells
Cytotoxicity against human HT1080 cells
|
[PMID: 2045815] |
| KB | ED50 |
13.3 μg/mL
Compound: 1
|
Cytotoxicity against vincristine-resistant human KB cells
Cytotoxicity against vincristine-resistant human KB cells
|
[PMID: 2045815] |
| KB | ED50 |
9.4 μg/mL
Compound: 1
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 2045815] |
| Lu1 | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human Lu1 cells
Cytotoxicity against human Lu1 cells
|
[PMID: 2045815] |
| P388 | ED50 |
5.9 μg/mL
Compound: 1
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 2045815] |
| SK-MEL-2 | ED50 |
14.6 μg/mL
Compound: 1
|
Cytotoxicity against human SK-MEL-2 cells
Cytotoxicity against human SK-MEL-2 cells
|
[PMID: 2045815] |
Chemical Information
-
CAS No. 133342-90-2
-
분자량 316.35
-
화학식 C18H20O5
-
SMILES
OC1=CC([C@@H]2CCC3=CC=C(OC)C=C3O2)=CC(OC)=C1OC
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)