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Cat. No.: HY-132906

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Antimalarial agent 3

Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC₅₀ = 0.035 μM) and has a very high selectivity index with respect to mammalian cells.

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CAS No.: 3033386-12-5
화학식: C₁₅H₁₆BrN₃O₂
분자량:350.21

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Antimalarial agent 3 Chemical Structure

CAS No.: 3033386-12-5

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC₅₀ = 0.035 μM) and has a very high selectivity index with respect to mammalian cells.

IC₅₀ & Target

Plasmodium

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
BMDM	IC₅₀	40 μM Compound: 12	Cytotoxicity against mouse BMDM cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against mouse BMDM cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 34795860]

Chemical Information

CAS No. 3033386-12-5
분자량 350.21
화학식 C₁₅H₁₆BrN₃O₂
SMILES

CC(C1=CC=C(C2=NN=C(C3CC(Br)=NO3)O2)C=C1)(C)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Galbiati A, et al. Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds. ACS Med Chem Lett. 2021 Oct 13;12(11):1726-1732. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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수량:
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Antimalarial agent 3

All Parasite Isoforms