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Cat. No.: HY-118803

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AS1468240

AS1468240 is an orally active inhibitor for anticoagulant factor Xa (fXa), that inhibits human fXa with IC₅₀ of 8.7 nM. AS1468240 prolongs the coagulation time in mice.

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CAS No.: 365462-61-9
화학식: C₂₅H₂₅Cl₂N₅O₃
분자량:514.40

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

AS1468240 Chemical Structure

CAS No.: 365462-61-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

AS1468240 is an orally active inhibitor for anticoagulant factor Xa (fXa), that inhibits human fXa with IC₅₀ of 8.7 nM. AS1468240 prolongs the coagulation time in mice^[1].

Chemical Information

CAS No. 365462-61-9
분자량 514.40
화학식 C₂₅H₂₅Cl₂N₅O₃
SMILES

O=C(C1=CC(Cl)=CC(O)=C1NC(C2=CC=C(C=C2)N3CCN(CCC3)C)=O)NC4=NC=C(C=C4)Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ishihara T, et al., Identification of potent orally active factor Xa inhibitors based on conjugation strategy and application of predictable fragment recommender system. Bioorg Med Chem. 2015 Jan 15;23(2):277-89. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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