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Cat. No.: HY-128126

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B-TPMF

B-TPMF is a selective inhibitor of the KCa2.1 channel, with an IC₅₀ of 30 nM, and it has a competitive functional interaction with CM-TPMF.

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CAS No.: 477865-65-9
화학식: C₁₉H₂₄N₆O₂
분자량:368.43

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

B-TPMF Chemical Structure

CAS No.: 477865-65-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

B-TPMF is a selective inhibitor of the KCa2.1 channel, with an IC₅₀ of 30 nM, and it has a competitive functional interaction with CM-TPMF^[1].

Chemical Information

CAS No. 477865-65-9
분자량 368.43
화학식 C₁₉H₂₄N₆O₂
SMILES

CON/C=N/C1=NN2C(C(OC3=CC=C(C(C)(C)C)C=C3)C)=CC=NC2=N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Charlotte Hougaard, et al. Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1 subtype. Mol Pharmacol. 2012 Feb;81(2):210-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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