Bacillibactin
Based on 1 Customer Validation
Bacillibactin (Corynebactin) is a cyclic tricatecholate siderophore. Bacillibactin’s primary function is to facilitate bacterial iron acquisition by chelating iron ions (Fe3+) from the environment, thereby aiding bacterial survival under iron-limited conditions. Bacillibactin exhibits direct antimicrobial activity, such as inhibition of the growth of the producing bacteria Pseudomonas aeruginosa and Aeromonas veronae, as well as plant pathogens such as Pseudomonas syringae.Bacillibactin can be used in antibacterial and antifungal research.
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- Purity: 98.1%
- CAS No.: 95536-41-7
- 화학식: C39H42N6O18
- 분자량:882.78
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Bacillibactin demonstrates strong inhibitory activity against Pseudomonas aeruginosa and Aeromonas veronii[1].
Bacillibactin significantly inhibites the growth of P. syringae pv. tomato, Pst under iron starvation conditions and inhibits the growth of a wider range of fungal pathogens (Such as Fusarium, Rhizoctonia, Aspergillus, Verticillium, etc.)[3].
Bacillibactin (10 μM) shows an inhibition rate of less than 20% against two human cancer cell lines (HepG2 liver cancer cells and MCF7 breast cancer cells), indicating that it does not exhibit significant in vitro anti-tumor activity[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 95536-41-7
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Appearance Solid
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분자량 882.78
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화학식 C39H42N6O18
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SMILES
O=C(C1=C(C(O)=CC=C1)O)NCC(N[C@H]2[C@H](OC([C@H]([C@H](OC([C@H]([C@H](OC2=O)C)NC(CNC(C3=C(C(O)=CC=C3)O)=O)=O)=O)C)NC(CNC(C4=C(C(O)=CC=C4)O)=O)=O)=O)C)=O
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Synonyms
Corynebactin
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Structure Classification
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Initial Source
Brevibacterium sp.
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
순도&문서
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Prazdnova E, et al. Bacillibactin, a Potential Bacillus-Based Antibacterial Non-Ribosomal Peptide: In Silico Studies for Targeting Common Fish Pathogens. Int J Mol Sci. 2025 Jun 17;26(12):5811. [Content Brief]
[2]. Pi H, Helmann JD. Genome-Wide Characterization of the Fur Regulatory Network Reveals a Link between Catechol Degradation and Bacillibactin Metabolism in Bacillus subtilis. mBio. 2018 Oct 30;9(5):e01451-18. [Content Brief]
[3]. Dimopoulou A, et al. Direct Antibiotic Activity of Bacillibactin Broadens the Biocontrol Range of Bacillus amyloliquefaciens MBI600. mSphere. 2021 Aug 25;6(4):e0037621. [Content Brief]
[4]. Zhou M, et al. Bacillibactin and Bacillomycin Analogues with Cytotoxicities against Human Cancer Cell Lines from Marine Bacillus sp. PKU-MA00093 and PKU-MA00092. Mar Drugs. 2018 Jan 10;16(1):22. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bacillibactin Related Classifications
HY-160238 Related Classifications
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