BBMP
BBMP is a permeability transition pore (PTP) inhibitor. BBMP prevents Ca2+-induced permeability transition and mitochondrial depolarization. BBMP possess potential for the neurodegenerative disorders research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 97120-13-3
- 화학식: C12H11BrN2O3S
- 분자량:343.20
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
제품 설명
In Vitro
BBMP is effective in both swelling and membrane potential assays displaying pIC50 values of 5.5 and 5.6, respectively. BBMP dose-dependently prevents DNA fragmentation induced by KCl 25/5 mM shift and serum deprivation in cerebellar granule neurons with a pIC50 of 5.7. The inhibition of PTP-mediated cytochrome c release observed in isolated mitochondria at 10 and 100 μM may explain its neuroprotective properties in vitro[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 97120-13-3
-
분자량 343.20
-
화학식 C12H11BrN2O3S
-
SMILES
O=C1C(Br)=C(S(=O)(CC2=CC=CC=C2)=O)C=NN1C
-
Synonyms
5-(Benzylsulfonyl)-4-bromo-2-methyl-3(2H)-pyridazinone
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BBMP Related Classifications
HY-108984 Related Classifications
Powered by Bioz