Bintrafusp alfa
Based on 1 Customer Validation
Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 97.96%
- CAS No.: 1918149-01-5
- 분자량:177.21 kDa
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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RepSox (GMP)TGF-β-RI/ALK5 Inhibitor (GMP) -
HY-P990957
Ficerafusp alfaAnti-EGFR/TGFβ Antibody
Biological Activity
제품 설명
Isotype
Human IgG1 lambda
Recommend Isotype Controls
In Vitro
Bintrafusp alfa can confer long-term protective immunity, decrease regulatory T-cell function, substantially increase CD8+ T cell and natural killer cell infiltration, and decrease myeloid-derived suppressor cell infiltration within tumors[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Human IgG1 lambda
신청
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 1918149-01-5
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Appearance Liquid
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분자량 177.21 kDa
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Color Colorless to light yellow
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SMILES
[Bintrafusp alfa]
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Synonyms
M7824; MSB0011359C
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선적
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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Data Sheet (256 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bintrafusp alfa Related Classifications
HY-P99480 Related Classifications
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