Boc-GABA-OH
Based on 1 Customer Validation
Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.14%
- CAS No.: 57294-38-9
- 화학식: C9H17NO4
- 분자량:203.24
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
All PROTAC Linkers Isoforms
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Biological Activity
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Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 57294-38-9
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Appearance Solid
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분자량 203.24
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화학식 C9H17NO4
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Color White to off-white
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SMILES
O=C(O)CCCNC(OC(C)(C)C)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
용액&용해도
DMSO : ≥ 100 mg/mL (492.03 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9203 mL | 24.6015 mL | 49.2029 mL | 123.0073 mL |
| 5 mM | 0.9841 mL | 4.9203 mL | 9.8406 mL | 24.6015 mL | |
| 10 mM | 0.4920 mL | 2.4601 mL | 4.9203 mL | 12.3007 mL | |
| 15 mM | 0.3280 mL | 1.6401 mL | 3.2802 mL | 8.2005 mL | |
| 20 mM | 0.2460 mL | 1.2301 mL | 2.4601 mL | 6.1504 mL | |
| 25 mM | 0.1968 mL | 0.9841 mL | 1.9681 mL | 4.9203 mL | |
| 30 mM | 0.1640 mL | 0.8200 mL | 1.6401 mL | 4.1002 mL | |
| 40 mM | 0.1230 mL | 0.6150 mL | 1.2301 mL | 3.0752 mL | |
| 50 mM | 0.0984 mL | 0.4920 mL | 0.9841 mL | 2.4601 mL | |
| 60 mM | 0.0820 mL | 0.4100 mL | 0.8200 mL | 2.0501 mL | |
| 80 mM | 0.0615 mL | 0.3075 mL | 0.6150 mL | 1.5376 mL | |
| 100 mM | 0.0492 mL | 0.2460 mL | 0.4920 mL | 1.2301 mL |