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Cat. No.: HY-125055A

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CD08108

CD08108 is a selective MC1R full agonist with an EC₅₀ of 70 nM against hMC1R. CD08108 participates in the melanogenesis process. CD08108 promotes cell proliferation. CD08108 can be used in studies related to vitiligo, subcutaneous diseases and photosensitive diseases.

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CAS No.: 1417342-67-6
화학식: C₃₁H₃₈N₄O₄
분자량:530.67

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CD08108 Chemical Structure

CAS No.: 1417342-67-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
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Biological Activity

제품 설명

IC₅₀ & Target^[2]

MC1R

70 nM (EC₅₀)

MC4R

4500 nM (EC₅₀)

All Melanocortin Receptor Isoforms :

In Vitro

CD08108 acts as a selective hMC1R agonist with an EC₅₀ of 70 nM, showing 64-fold higher potency for hMC1R compared to hMC4R^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1417342-67-6
분자량 530.67
화학식 C₃₁H₃₈N₄O₄
SMILES

O(CC1CC1)C2(CN(C([C@@H](CC3=CC=C(OC)C=C3)NC(CCC=4NC=NC4C)=O)=O)C2)C5=C(C)C=CC=C5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Boiteau J G, et al. Development of a Kilogram-Scale Synthesis of a Novel MC1R Agonist[J]. Organic Process Research & Development, 2015, 19(6): 646-651.

[2]. Mun Y, et al. Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects. Int J Mol Sci. 2023;24(15):12152. Published 2023 Jul 29. [Content Brief]

[3]. Mun Y W, et al. Melanocortin 1 Receptor (MC1R): Potentials as therapeutic targets[J]. 2023.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
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- In Vitro
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CD08108

All Melanocortin Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CD08108 Related Classifications

HY-125055A Related Classifications