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Cemtirestat

(Synonyms: CMTI)
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Cemtirestat (CMTI) is a carboxymethylated thiatriazinoindole inhibitor of aldose reductase (ALR2). Cemtirestat potently inhibits rat ocular lens ALR2 with an IC50 of 0.116 μM, and exhibits a 302-fold selectivity for rat kidney ALR1. Cemtirestat is applicable to the research of advanced diabetic complications.

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  • CAS No.: 309283-89-4
  • 화학식: C11H8N4O2S
  • 분자량:260.27
  • 보관:

    4°C, stored under nitrogen

    * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

  • Cemtirestat Chemical Structure
    Cemtirestat Chemical Structure
CAS No.: 309283-89-4
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