CoelPhos
CoelPhos is the cell-impermeable coelenterazine derivative. CoelPhos specifically recognizes extracellular GLuc and generates luminescent signals. CoelPhos is a practical bioluminescent tool for monitoring exocytic processes such as cell surface membrane fusion.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1643661-02-2
- 화학식: C33H33N6O7P
- 분자량:656.62
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
CoelPhos generates a detectable bioluminescent signal in HeLa cells expressing outer membrane-localized GLucM23, with an activity approximately 3-4% of that of native coelenterazine[1].
CoelPhos cannot cross the cell membrane, as it fails to generate a bioluminescent signal in HeLa cells expressing endoplasmic reticulum-localized GLucER[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1643661-02-2
-
분자량 656.62
-
화학식 C33H33N6O7P
-
SMILES
O=C1C(CC2=CC=C(C=C2)OCCCN3N=NC(COCP(O)(O)=O)=C3)=NC4=C(CC5=CC=CC=C5)NC(C6=CC=C(O)C=C6)=CN14
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)