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Cat. No.: HY-D1053

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CY7-N3

Name: CY7-N3
Brand: MedChemExpress
SKU: HY-D1053
Price: 400.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Sulfo-Cyanine7-N3)

1 Cited Publications

고객리뷰

Based on 1 publication(s) in Google Scholar

CY7-N3 (Sulfo-Cyanine7-N3) is a cyanine7 azide fluorescent dye and clickable quencher. CY7-N3 quenches the fluorescence of unreacted Cy5-DBCO, serves as a click chemistry quencher in the organelle-selective click labeling combined with flow cytometry (O-ClickFC) procedure for alkyne-labeled Palmitic acid (HY-N0830) in hematopoietic stem and progenitor cells, and can serve as a prodrug model loaded into DNAzyme-gated mesoporous Silicon dioxide (HY-W019831) nanoparticles. CY7-N3 can be used for click chemistry labeling and fluorescence imaging studies.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity : 97.32%
화학식: C₃₈H₄₇N₆O₇S₂
분자량:763.95

보관:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

CY7-N3 Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
- Emission (Em)
Chemical Information
Publications (1)
용액&용해도
- In Vitro
순도&문서
References
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

Lipid MetabolismMitochondrial FunctionOthers

Lipid Metabolism

Mitochondrial Function

CY7-N3 (100 nM; 3 cycles of 15 min at 37°C) quenches Cy5-DBCO after palmitate-azide labeling in lineage-depleted bone marrow cells, enabling flow cytometric assessment of mitochondrial fatty acid localization^[2].

Mitochondrial Function

CY7-N3 (Sulfo-Cyanine7-N3) (100 nM; 15 min) at 37°C is used as a quencher to eliminate unreacted Cy5-DBCO fluorescence after mitochondrial N3-PC labeling in K562 cells^[1].

Mitochondrial Function

Lipid Metabolism

CY7-N3 is used to quench unreacted Cy5-DBCO after click chemistry in live HeLa cells metabolically labelled with 19, enabling fluorescence imaging of mitochondrial 19-PE^[3].

Others

CY7-N3 is released by Mg²⁺/histidine-dependent DNAzyme activation in a cell-free mixture of DNAzyme-gated MP SiO₂ NPs and click-conjugated with Cy3-DBCO to form Cy3-Cy7^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Emission (Em)

785

Chemical Information

Appearance Solid
분자량 763.95
화학식 C₃₈H₄₇N₆O₇S₂
Color Green to dark green
SMILES

CC1(C)C(/C=C/C=C/C=C/C=C2N(CCCCCC(NCCCN=[N+]=[N-])=O)C(C=CC(S(=O)(O)=O)=C3)=C3C\2(C)C)=[N+]([CH+]C)C4=CC=C(S(=O)([O-])=[O-])C=C41
Synonyms

Sulfo-Cyanine7-N3
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Publications (1)

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Journal Impact Factor

bioRxiv

2026 Jun 8.

용액&용해도

In Vitro:

DMSO : 100 mg/mL (130.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.3090 mL

6.5449 mL

13.0899 mL

5 mM

0.2618 mL

1.3090 mL

2.6180 mL

10 mM

0.1309 mL

0.6545 mL

1.3090 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (279 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tsuchiya M, et al. Organelle-selective click labeling coupled with flow cytometry allows pooled CRISPR screening of genes involved in phosphatidylcholine metabolism. Cell metabolism. 2023 Jun 06;35(6):1072-1083.e9. [Content Brief]

[2]. Jones MA, et al. ACC1-Dependent De Novo Lipogenesis Sustains Hematopoietic Stem Cell Quiescence and Self-Renewal. bioRxiv. 2026 Jun 8:2026-06.

[3]. Biswal S, et al. A metabolic labelling-based lipid imaging technology establishes VPS13A as a phosphatidylethanolamine lipid transfer protein. bioRxiv. 2026 Jun 10:2026-06.

[4]. Vázquez-González M, et al. DNA-Responsive SiO Nanoparticles, Metal-Organic Frameworks, and Microcapsules for Controlled Drug Release. Langmuir : the ACS journal of surfaces and colloids. 2018 Dec 11;34(49):14692-14710.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.3090 mL	6.5449 mL	13.0899 mL	32.7247 mL
	5 mM	0.2618 mL	1.3090 mL	2.6180 mL	6.5449 mL
	10 mM	0.1309 mL	0.6545 mL	1.3090 mL	3.2725 mL
	15 mM	0.0873 mL	0.4363 mL	0.8727 mL	2.1816 mL
	20 mM	0.0654 mL	0.3272 mL	0.6545 mL	1.6362 mL
	25 mM	0.0524 mL	0.2618 mL	0.5236 mL	1.3090 mL
	30 mM	0.0436 mL	0.2182 mL	0.4363 mL	1.0908 mL
	40 mM	0.0327 mL	0.1636 mL	0.3272 mL	0.8181 mL
	50 mM	0.0262 mL	0.1309 mL	0.2618 mL	0.6545 mL
	60 mM	0.0218 mL	0.1091 mL	0.2182 mL	0.5454 mL
	80 mM	0.0164 mL	0.0818 mL	0.1636 mL	0.4091 mL
	100 mM	0.0131 mL	0.0654 mL	0.1309 mL	0.3272 mL

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- In Vitro
- Emission (Em)
Chemical Information
Publications (1)
용액&용해도
- In Vitro
순도&문서
References

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CY7-N3

Publications Citing Use of MedChemExpress (MCE) CY7-N3