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Cat. No.: HY-186282

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DiPODS

DiPODS is a thiolate-targeted bioconjugation reagent with irreversible covalent binding activity. DiPODS can rebridge the broken disulfide bonds in antibodies/Fab fragments. DiPODS enables site-specific bioconjugation to generate homogeneous immunoconjugates. DiPODS can conjugate with various payloads via the primary amine at the end of its side chain. DiPODS is applicable to breast cancer-related research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2756320-37-1
화학식: C₂₃H₃₂N₆O₁₁S₂
분자량:632.66

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

DiPODS Chemical Structure

CAS No.: 2756320-37-1

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

In Vitro

Anti-cancer

FabHER2-DiPODS-FITC (0.8 mg/mL; 30 min) retains specific binding to HER2-positive BT474 human breast cancer cells and exhibits higher immunoreactivity than a non-site-specific lysine-conjugated analogue^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Breast Cancer Modeling

Chemical Information

CAS No. 2756320-37-1
분자량 632.66
화학식 C₂₃H₃₂N₆O₁₁S₂
SMILES

O=C(CCOCCOCCOCCOCCN)NC1=CC(C2=NN=C(S(=O)(C)=O)O2)=CC(C3=NN=C(S(=O)(C)=O)O3)=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Khozeimeh Sarbisheh E, et al. DiPODS: A Reagent for Site-Specific Bioconjugation via the Irreversible Rebridging of Disulfide Linkages. Bioconjugate chemistry. 2020 Dec 16;31(12):2789-2806. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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