EBOV-IN-7
EBOV-IN-7 (compound 26) is an inhibitor of the Ebola virus EBOV with an IC50 of 2.04 μM against EBOV-GP pseudotyped virus (pEBOV). EBOV-IN-7 has inhibitory effects on cancer cells and inhibits the EBOV-GPcl/NPC1 interaction.
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- CAS No.: 68207-16-9
- 화학식: C18H19ClN4O3S
- 분자량:406.89
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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EBOV |
EBOV-IN-7 (compound 26) has a CC50 of 60 μM on HeLa cells and low cytotoxicity on Vero cells with a CC50 >100 μM[1].
EBOV-IN-7 (50 μM) significantly interferes with EBOV - GPcl/NPC1 interaction, IC50 against EBOV-GP-pseudotyped virus (pEBOV) is 2.04 μM[1].
EBOV-IN-7 IC50 against African swine fever virus ASFV is 15.75 μM[1].br /
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 68207-16-9
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분자량 406.89
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화학식 C18H19ClN4O3S
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SMILES
O=C(NNC1=CC=CC=C1SC2=CC(Cl)=CC=C2[N+]([O-])=O)CN3CCCC3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)