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Cat. No.: HY-184950

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eEF2K ligand-1

eEF2K ligand-1 is a PROTAC target protein ligand that targets eEF2K, and it is applicable to research related to PROTAC synthesis. eEF2K ligand-1 serves as the target protein of PROTAC eEF2K degrader-1 (HY-146324).

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CAS No.: 2458170-55-1
화학식: C₁₀H₁₁N₅O₃
분자량:249.23

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

eEF2K ligand-1 Chemical Structure

CAS No.: 2458170-55-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
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Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

CaMK III/eEF-2K

All CaMK Isoforms :

In Vitro

eEF2K ligand-1 serves as the target protein for PROTAC eEF2K degrader-1 (HY-146324). PROTAC eEF2K Degrader-1 (Compound 11l) is a PROTAC small molecule targeting eEF2K, which mediates eEF2K degradation and induces apoptosis in MDA-MB-231 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2458170-55-1
분자량 249.23
화학식 C₁₀H₁₁N₅O₃
SMILES

O=C(C1=C(N)N=C(C(C(N2)=O)=C1)N(CC)C2=O)N
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Liu Y, et al. Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells. European Journal of Medicinal Chemistry. 2020;204:112505.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
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순도&문서
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eEF2K ligand-1

All CaMK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

eEF2K ligand-1 Related Classifications

HY-184950 Related Classifications