F092
Based on 1 Customer Validation
F092 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS) with a KD value of 0.14 nM. F092 can be used in the study of allergic and inflammatory responses.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.79%
- CAS No.: 2250261-59-5
- 화학식: C20H17N5O2
- 분자량:359.38
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
제품 설명
IC50 & Target
KD: 0.14 nM (H-PGDS)[1].
Chemical Information
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CAS No. 2250261-59-5
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Appearance Solid
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분자량 359.38
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화학식 C20H17N5O2
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Color White to off-white
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SMILES
O=C(C1=CN=C(C2=NC=CC=C2)N=C1)NC3=CC=C(N4C(CCC4)=O)C=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
In Vitro:
DMSO : 125 mg/mL (347.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7826 mL | 13.9128 mL | 27.8257 mL | 69.5642 mL |
| 5 mM | 0.5565 mL | 2.7826 mL | 5.5651 mL | 13.9128 mL | |
| 10 mM | 0.2783 mL | 1.3913 mL | 2.7826 mL | 6.9564 mL | |
| 15 mM | 0.1855 mL | 0.9275 mL | 1.8550 mL | 4.6376 mL | |
| 20 mM | 0.1391 mL | 0.6956 mL | 1.3913 mL | 3.4782 mL | |
| 25 mM | 0.1113 mL | 0.5565 mL | 1.1130 mL | 2.7826 mL | |
| 30 mM | 0.0928 mL | 0.4638 mL | 0.9275 mL | 2.3188 mL | |
| 40 mM | 0.0696 mL | 0.3478 mL | 0.6956 mL | 1.7391 mL | |
| 50 mM | 0.0557 mL | 0.2783 mL | 0.5565 mL | 1.3913 mL | |
| 60 mM | 0.0464 mL | 0.2319 mL | 0.4638 mL | 1.1594 mL | |
| 80 mM | 0.0348 mL | 0.1739 mL | 0.3478 mL | 0.8696 mL | |
| 100 mM | 0.0278 mL | 0.1391 mL | 0.2783 mL | 0.6956 mL |